An updated framework for SARS-CoV-2 variants reflects the unpredictability of viral evolution

Throughout the COVID-19 pandemic, SARS-CoV-2 variants have been designated as variants of concern (VOCs) and variants of interest (VOIs) on the basis of their potential to replace previously circulating variants and cause new waves of increased transmission globally; such variants may require adjustments in public health responses. During the first two years of the pandemic, four VOCs and eight VOIs were designated by the World Health Organization (WHO), and these were overall closely related to the index virus.

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Publication
Contributors
Subissi L, Otieno JR, Worp N, Cohen HA, Munnink BBO, Abu-Raddad LJ, Alm E, Barakat A, Barclay WS, Bhiman JN, Caly L, Chand M, Chen M, Cullinane A, Oliveira TD, Drosten C, Druce J, Effler P, Masry IE, Faye A, Ghedin E, Grant R, Haagmans BL, Happi C, Herring BL, Hodcroft EM, Ikejezie J, Katawera V, Kassamali ZA, Leo YS, Leung GM, Kondor R, Marklewitz M, Mendez-Rico J, Melhem NM, Muster V, Nahapetyan K, Naindoo D, Oh DY, Peacock TP, Peiris M, Peng Z, Poon LLM, Rambaut A, Saha S, Shen Y, Siqueira MM, Volz E, Tessema SK, Thiel V, Triki H, Werf SVD, Eije KV, Cunningham J, Koopmans MPG, Gottberg AV, Agrawal A, Kerkhove MDV
Year
2024
Journal
Nature Medicine
Volume
30
Issue
9
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